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When is the best time of day to take Kratom?

“When is the best time of day to take Kratom?”

With the recent explosion in popularity, many customers will buy kratom online for the first time in the coming months.  One of the first questions these new kratom users ask is, “When is the best time of day to take kratom?”  It’s a great question and there are many factors to consider before you’ll be able to answer that for yourself.  The time of day you decide to take Kratom will be influenced by what you’re looking to achieve and the strain of kratom you’re taking.  There is no one-size fits all answer for the best time to take Kratom because that depends on the desired outcome.  However, once you are clear on your goals for taking Kratom this article will help you decide which Kratom strain is best for you as well as the optimal time to take it given your desired outcome.  To be able to fully answer this question for yourself let’s first get straight on what Kratom is and how it works in the body.

“First of all….When I buy Kratom Online what exactly am I getting and where does it come from?

 Kratom or its scientific name, Mitragyna speciosa is a herbal leaf from a tree of the Rubiaceae family which is a tropical evergreen tree that is in the coffee family and is native to Southeast Asia.  The tree can grow up to 82 feet tall and generally has a circumference of about 3 feet.  It mainly grows in Thailand, Indonesia, Malaysia, Myanmar, and Papa New Guinea.  It’s been used in these regions since at least the 19th century and is prized for both its sedative and stimulant-like effects.

This combination of a stimulant-like effect, combined with the sedative and pain-relieving properties of kratom made it ideal for farmers or manual laborers who are working long days in harsh conditions.  These properties make it a great aid for not only manual labor, but also to help those of us deal with the stresses, pressures, and difficulties we all face in the modern world as well.

As all-natural remedies gain popularity in the west, the use of kratom has also increased in lockstep with this trend.  As demand increases many new companies are popping up and offer consumers a wide variety of choice and selection in terms of where they can buy kratom online.  However, it’s always best to do your homework and only purchase your kratom from reputable vendors like Kratom Depot where you know the product is pure, unadulterated, and of the highest quality.

How does Kratom Work?

To understand and get some clarity on the best time of day to take kratom it helps to understand how it works once consumed.  While we know some things about what makes kratom work in the human body there are still many facets of this botanical that are still largely unknown.  There isn’t a ton of research out there on Kratom and much of the research is still ongoing, but here’s what we do know:

Kratom consists of over 40 biologically active compounds.  The most notable of these compounds are mitragynine, mitragynine pseudoindoxyl as well as its major metabolite 7-Hydroxymitragynine (referred to as 7-HMG).  Given that Kratom can be consumed in multiple forms the way your product is processed (whole leaf, powder, capsule, tablet, tea) can affect the ultimate composition and proportions of each of these compounds.

The actual effects one can expect when consuming kratom can vary greatly.  The biggest factors in the end result are based on the kratom’s potency (% of mitagynine), the form factor It was taken in (Capsule, Powder, whole leaf, tablet, tea) as well as the user’s body chemistry at the time of ingestion.  Given our body chemistry changes throughout the day, time of ingestion will play a role in the ultimate effect.

Kratom has long been known for its pain-killing properties and those are facilitated by u-opioid receptor stimulation.  In addition, Mitragynine and its metabolites will also interact with various neurotransmitters as well as non-opioid receptors within the nervous system.  This process is what gives Kratom its well-known stress-relieving and muscle-relaxing properties.  On the other side of the coin Kratom also has some very notable stimulant effects when used in lower doses.  We’ll examine how these dueling effects (Stimulation and Sedation) are both possible.

How does Kratom work as a Stimulant? 

When taken in low doses Kratom can be used as a stimulant and it’s one of the main reasons customers use the botanical.  Stimulant effects include increased energy, heart rate, metabolism, decreased appetite, and subsequent weight loss.  We still have a long way to go before we definitively understand how these processes work from a biologic perspective, but it’s speculated that the stimulant effects of Kratom are more than likely the result of mitragynine’s effects on neurotransmitters like dopamine, norepinephrine, and serotonin.

What’s unique about Kratom is that when taken in smaller doses it indeed exhibits stimulant-like effects, but when the dose increases or other biologic factors shift as happens throughout the day Kratom will produce effects that are the opposite of stimulants and act much more like a sedative.  This is important to keep in mind when thinking about the best time of day to take Kratom.

If you buy Kratom online, you’ll want to purchase the white strains of Kratom.  They are most notable with regard to increased energy and overall stimulation.  Some of the most notable stimulant effects are:

  • Euphoria
  • Sense of well-being
  • Decreased Appetite
  • Increased Energy and Stamina
  • Increased Ability to Focus
  • Slight tingling in extremities
  • Increased Confidence
  • Increase in Heart rate and Respiration

How Does Kratom Work as a Pain-Killing Sedative? 

While not fully known, it seems likely that Mirtagynine is responsible for the stimulant-like effects of Kratom whereas 7-HMG and MPI are more than likely the reasons Kratom can also act like a sedative.  These compounds have been found to be much more potent than Morphine.  In fact, MPI is about 20 times as potent, and 7-HMG is around 13 times more potent than Morphine when evaluated as a pain killer.  When taken in medium to larger doses these compounds work by binding to receptors in the brain and supersede the stimulant-like effects that are produced by mitragynine.

The red stains of Kratom have the largest combination of alkaloids that are consistent with Kratom’s relaxing, sedative-like effects.  Examples of Kratom’s sedative effects are:

  • Reduction or Elimination of Pain and Discomfort
  • A general sense of calm and well being
  • Relaxed Muscles
  • Extreme Anxiety Reduction
  • Drowsiness

What are the Effects of Kratom on the Brain? 

From a biological standpoint, the effects of Kratom or Mitragynine are very complex and there is still much we need to learn.  As we covered above, Kratom can act as both a stimulant or a sedative depending on the dose taken, the time of ingestion as well as strain.  The aim of this article is to provide the reader with a guide on, “The best time of day to take kratom” and the information we’ve covered so far is laying the foundation for our recommendations.

When considering the best time of day to take kratom, it’s good to be clear on why you are taking Kratom in the first place.  For instance, if you want to get energy for an intense workout your goals with kratom would be much different than if you wanted something to help you relax or get some sleep.  Kratom can help with both, but you’d want to use different strains at different times depending on which outcome you’re looking for.

The effects of different strains are due to the proportions of Mitragynine, 7-HMG, their effects on various receptors as well as how they are metabolized in the body.  Mitragynine mildly stimulates neural receptors normally associated with sedation but also interacts with serotonin and norepinephrine.  Typically, 7-HMG is more effective at stimulating neural receptors associated with sedation than mitagynine and research shows that 7-HMG is not only present in raw Kratom leaves, but also is produced as the body metabolizes mitragynine.  This helps explain Kratom’s pain-killing properties.  This is further proven in experiments where mitragynine is injected into mice vs taking Kratom orally.  There is always more 7-HMG when taken orally vs injection as it’s also a by-product of mitragynine metabolism.  Another factor to keep in mind when deciding when the best time is to take Kratom.

 The best time to take Kratom for Energy:  If you are taking Kratom for a pickup and want some energy the best time of day to take your dose would be in the morning.  Research shows that our body secretes cortisol as a means of waking us up.  This begins while we are still asleep and then ends an hour or so after we wake.  It’s always best to align with our body’s natural rhythms so it’s advisable to let this play out and then take your Kratom about an hour or so after you rise to wait for the cortisol cycle to run its course.  Also remember, that when you are going for a stimulant effect take a smaller Kratom dose than you may normally otherwise take due to the scientific reasons discussed in this article.  Of equal importance:  When taking Kratom as a stimulant make sure to take one of the green or preferably a white strain.  We highly recommend White Maeng Da as the best Kratom Strain for Energy.  Lastly, for optimal absorption, we’d also suggest taking Kratom on an empty stomach.  If that isn’t possible, make sure you at least have only had a light breakfast.

The best time of day to take Kratom for Stress Relief:  This is a bit more complicated to answer.  From an absorption perspective, Kratom will normally be the most effective and bio-available in the morning on an empty stomach.  However, we realize stress can come on at any time during the day.  The good news is that Kratom can also work at any time of day.  The key is to make sure your stomach is relatively empty to ensure optimal absorption.  For stress relief, it’s advisable to take Kratom mid-morning/early afternoon or right before dinner.  Always on an empty stomach.  However, if you know you will be stressed at certain times you can build your meal plan around that to make sure you’re taking Kratom in between meals.  For stress relief, we highly recommend starting with Red Maeng Da Kratom.   You can’t go wrong.

Summary & Conclusion

There are several factors to keep in mind when considering when to take Kratom for optimal results.  The first is to fully think through why you are taking Kratom and understand your reasons.  Secondly, you’ll want to choose a time when your stomach is relatively empty so you know all the Kratom ingested will be absorbed.  And finally, you’ll want to make sure you choose the right strain given your desired effect.  If you buy Kratom online, we encourage you to check out our full menu at Kratom Depot and be sure to read the product descriptions as they will help guide you in your kratom journey.  In summary, there are really no wrong times to take Kratom but if you use the information in this article you’ll be much more prepared to take Kratom the “right way”.

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